Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 Mar 1;15(2):126.
doi: 10.1186/cc10014.

Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!

Matthew J Reed  1 , Nazir Lone, Timothy S Walsh
Affiliations
Comment

Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!

Matthew J Reed et al. Crit Care. .

Abstract

The management of trauma-related coagulopathy and haemorrhage is changing from a reactive strategy to a proactive early intervention with blood products and haemostatic agents. Although major haemorrhage and massive transfusion are associated with higher mortality, the pattern of this association with modern trauma care is poorly described. In addition, early predictors of massive transfusion, which might trigger a proactive haemostatic resuscitation strategy, are not currently available. We review recent literature relating to predictors of massive transfusions and the relationship between transfusion and mortality.

PubMed Disclaimer

Comment on

  • Reappraising the concept of massive transfusion in trauma.
    Stanworth SJ, Morris TP, Gaarder C, Goslings JC, Maegele M, Cohen MJ, König TC, Davenport RA, Pittet JF, Johansson PI, Allard S, Johnson T, Brohi K. Stanworth SJ, et al. Crit Care. 2010;14(6):R239. doi: 10.1186/cc9394. Epub 2010 Dec 30. Crit Care. 2010. PMID: 21192812 Free PMC article.

References

    1. Stanworth SJ, Morris TP, Gaardner C, Goslings JC, Maegele M, Cohen MJ, Konig TC, Davenport RA, Pittet J-F, Johansson PI, Allard S, Johnson T, Brohi K. Reappraising the concept of massive transfusion in trauma. Crit Care. 2010;14:R239. doi: 10.1186/cc9394. - DOI - PMC - PubMed
    1. Rossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, Hunt BJ, Komadina R, Nardi G, Neugebauer E, Ozier Y, Riddez L, Schultz A, Stahel PF, Vincent J-L, Spahn DR. Management of bleeding following major trauma: an updated European guideline. Crit Care. 2010;14:R52. doi: 10.1186/cc8943. - DOI - PMC - PubMed
    1. Brohi K, Singh J, Heron M, Coats T. Acute traumatic coagulopathy. J Trauma. 2003;54:1127–1130. doi: 10.1097/01.TA.0000069184.82147.06. - DOI - PubMed
    1. Brohi K, Cohen MJ, Ganter MT, Matthay MA, Mackersie RC, Pittet JF. Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway? Ann Surg. 2007;245:812–818. doi: 10.1097/01.sla.0000256862.79374.31. - DOI - PMC - PubMed
    1. Gonzalez EQ. Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma. 2007;62:112–119. doi: 10.1097/01.ta.0000250497.08101.8b. - DOI - PubMed