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. 2011;59(3):353-8.
doi: 10.1248/cpb.59.353.

Cladieunicellins A-E, new eunicellins from an Indonesian soft coral Cladiella sp

Yung-Husan Chen  1 , Chia-Ying Tai, Yueh-Hsiung Kuo, Chia-Ying Kao, Jan-Jung Li, Tsong-Long Hwang, Lee-Shing Fang, Wei-Hsien Wang, Jyh-Horng Sheu, Ping-Jyun Sung
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Free article

Cladieunicellins A-E, new eunicellins from an Indonesian soft coral Cladiella sp

Yung-Husan Chen et al. Chem Pharm Bull (Tokyo). 2011.
Free article

Abstract

Five new eunicellin-type diterpenoids, cladieunicellins A-E (1-5), were isolated from an Indonesian soft coral identified as Cladiella sp. The structures of diterpenoids 1-5 were established using spectroscopic methods. Eunicellins 2 and 5 were found to be cytotoxic against DLD-1 and HL-60 tumor cells, respectively, and 3 displayed inhibitory effects against superoxide anion generation by human neutrophils.

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