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. 2011;59(3):407-11.
doi: 10.1248/cpb.59.407.

Ceramicines E-I, new limonoids from Chisocheton ceramicus

Chin Piow Wong  1 , Misae Shimada, Yuta Nagakura, Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, Khalijah Awang, A Hamid A Hadi, Khalit Mohamad, Motoo Shiro, Hiroshi Morita
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Free article

Ceramicines E-I, new limonoids from Chisocheton ceramicus

Chin Piow Wong et al. Chem Pharm Bull (Tokyo). 2011.
Free article

Abstract

Five new limonoids, ceramicines E-I (1-5), have been isolated from the bark of Chisocheton ceramicus. The structures and relative stereochemistry of them were fully elucidated based on 1D- and 2D-NMR data. Ceramicines E-I (1-5) exhibited moderate cell growth inhibitory activities on a range of cell lines (HL-60, A549, MCF7, and HCT116). The absolute structure of previously isolated ceramicine B (6) was also elucidated by circular dichroism (CD) and X-ray analysis.

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