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Case Reports
. 2011 Sep;30(9):810-2.
doi: 10.1097/INF.0b013e31821487f5.

Successful management of chronic multifocal Q fever Osteomyelitis with adjuvant interferon-gamma therapy

Olaf Werner Neth  1 , Dolores Falcon, Estrella Peromingo, Maria Soledad Camacho, Carlos Rodríguez-Gallego, Ignacio Obando
Affiliations
Case Reports

Successful management of chronic multifocal Q fever Osteomyelitis with adjuvant interferon-gamma therapy

Olaf Werner Neth et al. Pediatr Infect Dis J. 2011 Sep.

Abstract

We present a 3-year-old girl who had chronic recurrent multifocal osteomyelitis caused by Coxiella burnetii despite long-term dual antibiotic therapy. Excellent clinical response was achieved and sustained when immunomodulatory therapy with interferon-γ was initiated. This is the case of a first child who was successfully treated with interferon-γ as adjuvant therapy for chronic multifocal Q fever osteomyelitis.

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