[Biomaterials and vascular grafts]

Abstract

The latest articles concerning the vascular grafts made of biomaterials were retrieved and the data on application of electrospun biopolymer in small diameter vascular tissue engineering scaffolds were comprehensively analyzed. The biomaterials, including natural vascular, decellularized scaffolds and biopolymer in the field of vascular grafts were studied. But natural vascular grafts and decellularized scaffolds can not meet the requirements of small diameter vascular graft because of inadequate sources and potential immunogenicity, respectively. The small diameter vascular scaffolds prepared by electrospinning of biopolymer can optimally simulate the blood vessel structure and properties, and hence can present a better approach to acquiring small diameter vascular tissue engineering scaffolds.