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Comment
. 2011 Mar 4;144(5):642-3.
doi: 10.1016/j.cell.2011.02.028.

The skeleton: the new controller of male fertility?

Lee B Smith  1 , Philippa T K Saunders
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Free article
Comment

The skeleton: the new controller of male fertility?

Lee B Smith et al. Cell. .
Free article

Abstract

Sex steroids, including testosterone, regulate the development and function of the male skeleton. Oury et al. (2011) identify a surprising new connection between the skeleton and the testis, which has implications for male fertility. They show that testosterone production in the testis is directly influenced by the bone-derived hormone osteocalcin.

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  • Endocrine regulation of male fertility by the skeleton.
    Oury F, Sumara G, Sumara O, Ferron M, Chang H, Smith CE, Hermo L, Suarez S, Roth BL, Ducy P, Karsenty G. Oury F, et al. Cell. 2011 Mar 4;144(5):796-809. doi: 10.1016/j.cell.2011.02.004. Epub 2011 Feb 17. Cell. 2011. PMID: 21333348 Free PMC article.

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