Plasminogen activators: pharmacology and therapy
- PMID: 2137641
- DOI: 10.1148/radiology.174.3.174-3-993
Plasminogen activators: pharmacology and therapy
Abstract
Biochemical advances are providing new insights into coagulation and fibrinolysis. Integrating this biochemical knowledge into plasminogen activator therapy improves understanding of currently available enzymes. Basic components of the fibrinolytic system are discussed and the chemical structures, pharmacokinetics, dosages, and modes of delivery of current and future plasminogen activators are reviewed.
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