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Review
. 1990 Mar;174(3 Pt 2):993-1001.
doi: 10.1148/radiology.174.3.174-3-993.

Plasminogen activators: pharmacology and therapy

R W Holden  1
Affiliations
Review

Plasminogen activators: pharmacology and therapy

R W Holden. Radiology. 1990 Mar.

Abstract

Biochemical advances are providing new insights into coagulation and fibrinolysis. Integrating this biochemical knowledge into plasminogen activator therapy improves understanding of currently available enzymes. Basic components of the fibrinolytic system are discussed and the chemical structures, pharmacokinetics, dosages, and modes of delivery of current and future plasminogen activators are reviewed.

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