Review
doi: 10.1016/0002-9378(90)90436-b.
Comparison of the pharmacology of nafarelin and danazol
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- PMID: 2137975
- DOI: 10.1016/0002-9378(90)90436-b
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Review
Comparison of the pharmacology of nafarelin and danazol
Am J Obstet Gynecol.
1990 Feb.
Abstract
The pharmacologic profiles of danazol and nafarelin differ considerably from each other. Danazol interacts with multiple classes of proteins, whereas the gonadotropin-releasing hormone agonist nafarelin interacts only with the pituitary gonadotropin-releasing hormone receptor. Differences in the molecular, endocrine, and clinical pharmacologic properties of these agents may provide clues to their varying effects in the management of women with endometriosis.
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