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. 1990 Mar;69(3):454-9.

Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice

V Del Gobbo  1 , N Villani, S Marini, E Balestra, R Caliò
Affiliations

Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice

V Del Gobbo et al. Immunology. 1990 Mar.

Abstract

PR8 virus depressed interleukin-2 (IL-2) and natural killer (NK) cell activity in BALB/c infected mice. IL-2 production was not dependent on (i) a decreased number of T cells or (ii) a primary defect in IL-1 production, but on a T-suppressor cell subpopulation. In fact, when T suppressor cells were removed from infected spleen cells, we observed normal levels of IL-2 activity.

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