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Randomized Controlled Trial
. 2011 Mar 8:11:17.
doi: 10.1186/1471-2393-11-17.

Nutritional status of iodine in pregnant women in Catalonia (Spain): study on hygiene-dietetic habits and iodine in urine

Gemma Prieto  1 , Maria Teresa Torres, Lidia Francés, Gemma Falguera, Lluis Vila, Josep María Manresa, Roser Casamitjana, Juan Ramón Barrada, Amèlia Acera, Dolors Guix, Anna Torrent, Josep Grau, Pere Torán; IODEGEST study group
Collaborators, Affiliations
Randomized Controlled Trial

Nutritional status of iodine in pregnant women in Catalonia (Spain): study on hygiene-dietetic habits and iodine in urine

Gemma Prieto et al. BMC Pregnancy Childbirth. .

Abstract

Background: It is a priority to achieve an adequate nutritional status of iodine during pregnancy since iodine deficiency in this population may have repercussions on the mother during both gestation and post partum as well as on the foetus, the neonate and the child at different ages. According to the WHO, iodine deficiency is the most frequent cause of mental retardation and irrreversible cerebral lesions around the world. However, few studies have been published on the nutritional status of iodine in the pregnant population within the Primary Care setting, a health care level which plays an essential role in the education and control of pregnant women. Therefore, the aim of the present study is: 1.- To know the hygiene-dietetic habits related to the intake of foods rich in iodine and smoking during pregnancy. 2.- To determine the prevalence of iodine deficiency and the factors associated with its appearance during pregnancy.

Methods/design: We will perform a cluster randomised, controlled, multicentre trial. Randomisation unit: Primary Care Team.

Study population: 898 pregnant women over the age of 17 years attending consultation to a midwife during the first trimester of pregnancy in the participating primary care centres.

Outcome measures: consumption of iodine-rich foods and iodine deficiency. Points of assessment: each trimester of the gestation.

Intervention: group education during the first trimester of gestation on healthy hygiene-dietetic habits and the importance of an adequate iodine nutritional status.

Statistical analysis: descriptive analysis of all variables will be performed as well as multilevel logistic regression. All analyses will be done carried out on an intention to treat basis and will be fitted for potential confounding factors and variables of clinical importance.

Discussion: Evidence of generalised iodine deficiency during pregnancy could lead to the promotion of interventions of prevention such as how to improve and intensify health care educational programmes for pregnant women.

Trial registration: ClinicalTrials.gov: NCT01301768.

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References

    1. Morreale de Escobar G. In: Yodo y salud en el siglo XXI. European Pharmaceutical Law Group, editor. Madrid; 2004. Yodo y embarazo; pp. 107–108.
    1. Francés L, Torres MT. Déficit de yodo durante la gestación. Matronas profesión. 2003;11:37–43.
    1. Muñoz Márquez JA. In: Yodo y salud en el siglo XXI. European Pharmaceutical Law Group, editor. Madrid; 2004. Yodo y embarazo; pp. 177–216.
    1. WHO; UNICEF; ICCIDD. Assesment of the Iodine Deficiency Disorders and monitoring their elimination. Geneva: WHO publication. WHO/NHD/01.1; 2001. pp. 1–107. Geneve.
    1. Donnay Candil S. In: Yodo y salud en el siglo XXI. European Pharmaceutical Law Group, editor. Madrid; 2004. Enfermedades originadas por la deficiencia de yodo; pp. 145–175.

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