Streptosporangium oxazolinicum sp. nov., a novel endophytic actinomycete producing new antitrypanosomal antibiotics, spoxazomicins

Abstract

An actinomycete strain K07-0460(T) producing new antitrypanosomal antibiotics, spoxazomicins, was isolated from the roots of a variety of orchid collected in the subtropical Okinawa prefecture. The 16S ribosomal RNA gene sequence analysis indicated that the strain belonged to the genus Streptosporangium and showed high similarities with S. amethystogenes subsp. amethystogenes DSM 43179(T) (99.4%), S. amethystogenes subsp. fukuiense IFO 15365(T) (99.2%) and S. longisporum DSM 43180(T) (98.7%). The DNA-DNA hybridization relatedness values between strain K07-0460(T) and the three strains were below 70%. On the basis of phylogenetic analysis, DNA-DNA hybridization relatedness and physiological characteristics, the strain should be classified as a new species Streptosporangium oxazolinicum sp. nov. in the genus Streptosporangium. The type strain of S. oxazolinicum is K07-0460(T) (=JCM 17388(T)).