Hyperthyroidism in a case of Down syndrome

Abstract

An 18 years old mentally retarded male, with morphologic features suggestive of Down syndrome was admitted with fever since 3 weeks. Karyotyping proved trisomy 21. Prominent thyroid swelling with resting tachycardia and hyper-irritability was present. He was found to have multiple renal abscesses and was treated with antibiotics. Thyroid function tests revealed hyperthyroidism which responded to anti-thyroid drugs. So, we report this case of Down syndrome with hyperthyroidism which is a rare association.