Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Apr;100(3):340-2.
doi: 10.1111/j.1423-0410.2010.01412.x. Epub 2010 Sep 24.

Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors?

M A Beale  1 , K Tettmar, R Szypulska, R S Tedder, S Ijaz
Affiliations

Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors?

M A Beale et al. Vox Sang. 2011 Apr.

Abstract

Background and objective: The risk of hepatitis E virus (HEV) to blood safety remains unknown in England. Reports of persistent HEV infection with serious disease sequelae indicate that transfusion transmitted HEV is not a trivial disease in immunosuppressed patients.

Materials and methods: Samples from unselected blood donors and donors with a history of jaundice were tested for HEV antibody and RNA.

Results: Overall, 10% of the donor sera were anti-HEV IgG reactive. Four of the donor samples were anti-HEV IgM reactive but HEV RNA negative.

Conclusion: There is evidence of probable recent HEV infections in donors with a predicted attack rate of 2.8%.

PubMed Disclaimer

Publication types

LinkOut - more resources