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Review
. 2011 Mar;17(3):425-31.
doi: 10.3201/eid1703.101550.

Tuberculosis outbreak investigations in the United States, 2002-2008

Kiren Mitruka  1 , John E Oeltmann, Kashef Ijaz, Maryam B Haddad
Affiliations
Review

Tuberculosis outbreak investigations in the United States, 2002-2008

Kiren Mitruka et al. Emerg Infect Dis. 2011 Mar.

Abstract

To understand circumstances of tuberculosis transmission that strain public health resources, we systematically reviewed Centers for Disease Control and Prevention (CDC) staff reports of US outbreaks in which CDC participated during 2002-2008 that involved ≥3 culture-confirmed tuberculosis cases linked by genotype and epidemiology. Twenty-seven outbreaks, representing 398 patients, were reviewed. Twenty-four of the 27 outbreaks involved primarily US-born patients; substance abuse was another predominant feature of outbreaks. Prolonged infectiousness because of provider- and patient-related factors was common. In 17 outbreaks, a drug house was a notable contributing factor. The most frequently documented intervention to control the outbreak was prioritizing contacts according to risk for infection and disease progression to ensure that the highest risk contacts were completely evaluated. US-born persons with reported substance abuse most strongly characterized the tuberculosis outbreaks in this review. Substance abuse remains one of the greatest challenges to controlling tuberculosis transmission in the United States.

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References

    1. Centers for Disease Control and Prevention. Controlling tuberculosis in the United States: recommendations from the American Thoracic Society, CDC, and the Infectious Diseases Society of America. MMWR Morb Mortal Wkly Rep. 2005;54(RR-12):1–3. - PubMed
    1. Onorato IM. Tuberculosis outbreaks in the United States. Int J Tuberc Lung Dis. 2000;4(Suppl 2):S121–6. - PubMed
    1. Centers for Disease Control and Prevention. Public health dispatch: tuberculosis outbreak in a homeless population—Portland, Maine, 2002–2003. MMWR Morb Mortal Wkly Rep. 2003;52:1184. - PubMed
    1. Centers for Disease Control and Prevention. Transmission of Mycobacterium tuberculosis associated with failed completion of treatment for latent tuberculosis infection—Chickasaw County, Mississippi, June 1999–March 2002. MMWR Morb Mortal Wkly Rep. 2003;52:222–4. - PubMed
    1. Centers for Disease Control and Prevention. Public health dispatch: tuberculosis outbreak among homeless persons—King County, Washington, 2002–2003. MMWR Morb Mortal Wkly Rep. 2003;52:1209–10. - PubMed

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