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. 2011 Apr;15(4):547-50.
doi: 10.5588/ijtld.10.0140.

Standardised second-line treatment of multidrug-resistant tuberculosis during pregnancy

P Tabarsi  1 , A Moradi, P Baghaei, M Marjani, M Shamaei, N Mansouri, E Chitsaz, P Farnia, D Mansouri, M Masjedi, A Velayati
Affiliations

Standardised second-line treatment of multidrug-resistant tuberculosis during pregnancy

P Tabarsi et al. Int J Tuberc Lung Dis. 2011 Apr.

Abstract

We describe the efficacy and outcome of standardised second-line anti-tuberculosis (TB) medications during pregnancy. Treatment outcomes of five pregnant women with documented multidrug-resistant TB (MDR-TB) referred to the National Research Institute of Tuberculosis and Lung Diseases from 2003 to 2009 were analysed in two categories, maternal and neonatal. Patients became pregnant during treatment for MDR-TB without any changes in their anti-tuberculosis regimen. None of them had any adverse effects during pregnancy and delivery. No adverse effects were observed in mothers or neonates. The treatment of MDR-TB during pregnancy with a standardised second-line regimen in this study population was safe, with an acceptable rate of treatment success.

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