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Review
. 2011 Apr;33(2):112-22; quiz 123-6.
doi: 10.1097/DAD.0b013e3181fcfb47.

Pseudoepitheliomatous hyperplasia: a review

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Review

Pseudoepitheliomatous hyperplasia: a review

Maya Zayour et al. Am J Dermatopathol. 2011 Apr.

Abstract

Pseudoepitheliomatous hyperplasia (PEH) is a benign condition, characterized by hyperplasia of the epidermis and adnexal epithelium, closely simulating squamous cell carcinoma. PEH may be present in a number of conditions characterized by prolonged inflammation and/or chronic infection, as well as in association with many cutaneous neoplasms. Herein, we review different inflammatory, infectious, and neoplastic skin diseases, in which florid epidermal hyperplasia is a prominent histopathologic feature, and introduce a systematic approach in the interpretation of PEH.

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