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. 2011 Apr 21;47(15):4379-81.
doi: 10.1039/c1cc10751h. Epub 2011 Mar 28.

One-pot nitro-Mannich/hydroamination cascades for the direct synthesis of 2,5-disubstituted pyrroles using base and gold catalysis

David M Barber  1 , Hitesh Sanganee, Darren J Dixon
Affiliations

One-pot nitro-Mannich/hydroamination cascades for the direct synthesis of 2,5-disubstituted pyrroles using base and gold catalysis

David M Barber et al. Chem Commun (Camb). .

Abstract

An efficient, easy to perform, one-pot reaction cascade for the synthesis of 2,5-disubstituted pyrroles from p-toluenesulfonyl protected imines and 4-nitrobut-1-yne under a combination of base and gold(III) catalysis is reported.

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