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. 2011 Apr 21;47(15):4373-5.
doi: 10.1039/c1cc10589b. Epub 2011 Mar 14.

A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Xiaoqiang Chen  1 , Kyung-Ah Lee, Eun-Mi Ha, Kyung Mi Lee, You Yeong Seo, Han Kyoung Choi, Ha Na Kim, Min Jung Kim, Chun-Seok Cho, Soo Young Lee, Won-Jae Lee, Juyoung Yoon
Affiliations

A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Xiaoqiang Chen et al. Chem Commun (Camb). .

Abstract

A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

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