Host defenses trigger salmonella's arsenal
- PMID: 21402352
- DOI: 10.1016/j.chom.2011.03.003
Host defenses trigger salmonella's arsenal
Abstract
Salmonella survives in macrophages by using a molecular syringe to deliver proteins into the host-cell cytosol where they manipulate phagocyte physiology. Arpaia and colleagues (Arpaia et al., 2011) show that deployment of this virulence factor is triggered by the very responses that are intended to confer host resistance.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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TLR signaling is required for Salmonella typhimurium virulence.Cell. 2011 Mar 4;144(5):675-88. doi: 10.1016/j.cell.2011.01.031. Cell. 2011. PMID: 21376231 Free PMC article.
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