Preventing phagocytosis takes more than a sweet disposition
- PMID: 21402356
- DOI: 10.1016/j.chom.2011.03.006
Preventing phagocytosis takes more than a sweet disposition
Abstract
While a polysaccharide capsule is known to be important for preventing phagocytosis of the human pathogen Cryptococcus neoformans, other antiphagocytic pathways have been generally elusive. Now, a capsule-independent pathway has been identified that prevents macrophages from ingesting the fungus, contributing to evasion of the host immune response.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans.Cell Host Microbe. 2011 Mar 17;9(3):243-251. doi: 10.1016/j.chom.2011.02.003. Cell Host Microbe. 2011. PMID: 21402362 Free PMC article.
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