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Comment
. 2011 Mar 22;108(12):E43; author reply E44.
doi: 10.1073/pnas.1100419108. Epub 2011 Mar 14.

Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?

Klaus I Matthaei, Michael Frese, Caryl E Hill
Comment

Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?

Klaus I Matthaei et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Comment in

  • ADAR1 isoform involvement in embryonic lethality.
    Steinman RA, Wang Q. Steinman RA, et al. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):E199; author reply E200. doi: 10.1073/pnas.1105004108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593418 Free PMC article. No abstract available.

Comment on

References

    1. Ward SV, et al. RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis. Proc Natl Acad Sci USA. 2011;108:331–336. - PMC - PubMed
    1. Hartner JC, Walkley CR, Lu J, Orkin SH. ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. Nat Immunol. 2009;10:109–115. - PMC - PubMed
    1. George CX, Wagner MV, Samuel CE. Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing. J Biol Chem. 2005;280:15020–15028. - PubMed
    1. Grisendi S, et al. Role of nucleophosmin in embryonic development and tumorigenesis. Nature. 2005;437:147–153. - PubMed

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