Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?
- PMID: 21402945
- PMCID: PMC3064400
- DOI: 10.1073/pnas.1100419108
Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?
Conflict of interest statement
The authors declare no conflict of interest.
Comment in
-
ADAR1 isoform involvement in embryonic lethality.Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):E199; author reply E200. doi: 10.1073/pnas.1105004108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593418 Free PMC article. No abstract available.
Comment on
-
RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis.Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6. doi: 10.1073/pnas.1017241108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2011. PMID: 21173229 Free PMC article.
Similar articles
-
ADAR1 isoform involvement in embryonic lethality.Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):E199; author reply E200. doi: 10.1073/pnas.1105004108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593418 Free PMC article. No abstract available.
-
RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis.Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6. doi: 10.1073/pnas.1017241108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2011. PMID: 21173229 Free PMC article.
-
Infection of different cell lines of neural origin with subacute sclerosing panencephalitis (SSPE) virus.Microbiol Immunol. 2004;48(4):277-87. doi: 10.1111/j.1348-0421.2004.tb03524.x. Microbiol Immunol. 2004. PMID: 15107538
-
[Subacute sclerosing panencephalitis].Vopr Virusol. 1983 Nov-Dec;28(6):644-7. Vopr Virusol. 1983. PMID: 6367219 Review. Russian. No abstract available.
-
[Molecular mechanisms of persistent infection of subacute sclerosing panencephalitis (SSPE) viruses].Uirusu. 1988 Jun;38(1):23-57. doi: 10.2222/jsv.38.23. Uirusu. 1988. PMID: 3070924 Review. Japanese. No abstract available.
Cited by
-
Generation of a new Adar1p150 -/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis.RNA. 2023 Sep;29(9):1325-1338. doi: 10.1261/rna.079509.122. Epub 2023 Jun 8. RNA. 2023. PMID: 37290963 Free PMC article.
-
Mouse models for Aicardi-Goutières syndrome provide clues to the molecular pathogenesis of systemic autoimmunity.Clin Exp Immunol. 2014 Jan;175(1):9-16. doi: 10.1111/cei.12147. Clin Exp Immunol. 2014. PMID: 23713592 Free PMC article. Review.
-
ADAR1 isoform involvement in embryonic lethality.Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):E199; author reply E200. doi: 10.1073/pnas.1105004108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593418 Free PMC article. No abstract available.
-
Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line.Elife. 2017 Mar 31;6:e25687. doi: 10.7554/eLife.25687. Elife. 2017. PMID: 28362255 Free PMC article.
References
-
- George CX, Wagner MV, Samuel CE. Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing. J Biol Chem. 2005;280:15020–15028. - PubMed
-
- Grisendi S, et al. Role of nucleophosmin in embryonic development and tumorigenesis. Nature. 2005;437:147–153. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials