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Review
. 2011:2011:187103.
doi: 10.1155/2011/187103. Epub 2011 Feb 23.

Sex differences in drug disposition

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Review

Sex differences in drug disposition

Offie P Soldin et al. J Biomed Biotechnol. 2011.

Abstract

Physiological, hormonal, and genetic differences between males and females affect the prevalence, incidence, and severity of diseases and responses to therapy. Understanding these differences is important for designing safe and effective treatments. This paper summarizes sex differences that impact drug disposition and includes a general comparison of clinical pharmacology as it applies to men and women.

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References

    1. Legato MJ. Principles of Gender-Specific Medicine. Amsterdam, The Netherlands: Academic Press; 2010.
    1. Legato MJ, Bilezikian JP. Principles of Gender-Specific Medicine. Boston, Mass, USA: Elsevier Academic Press; 2004.
    1. Hamburg MA, Collins FS. The path to personalized medicine. New England Journal of Medicine. 2010;363(4):301–304. - PubMed
    1. Hardman JG, Limbird LE, Gilman AG. Goodman & Gilman's the Pharmacological Basis of Therapeutics. New York, NY, USA: McGraw-Hill; 2001.
    1. Soldin OP, Mattison DR. Sex differences in pharmacokinetics and pharmacodynamics. Clinical Pharmacokinetics. 2009;48(3):143–157. - PMC - PubMed

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