The frailty syndrome

doi:10.7861/clinmedicine.11-1-72

Review

. 2011 Feb;11(1):72-5.

doi: 10.7861/clinmedicine.11-1-72.

The frailty syndrome

Andrew Clegg¹, John Young

Affiliations

Affiliation

¹ Bradford Institute for Health Research, Temple Bank House, Bradford Teaching Hospitals NHS Foundation Trust, Duckworth Lane, Bradford. andrew.clegg@bradfordhospitals.nhs.uk

PMID: 21404792
PMCID: PMC5873811
DOI: 10.7861/clinmedicine.11-1-72

Review

The frailty syndrome

Andrew Clegg et al. Clin Med (Lond). 2011 Feb.

. 2011 Feb;11(1):72-5.

doi: 10.7861/clinmedicine.11-1-72.

Authors

Andrew Clegg¹, John Young

Affiliation

¹ Bradford Institute for Health Research, Temple Bank House, Bradford Teaching Hospitals NHS Foundation Trust, Duckworth Lane, Bradford. andrew.clegg@bradfordhospitals.nhs.uk

PMID: 21404792
PMCID: PMC5873811
DOI: 10.7861/clinmedicine.11-1-72

No abstract available

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Figures

**Fig 1.**
Vulnerability to sudden change in health state due to reduced functional reserve in frail older people. UTI = urinary tract infection

**Fig 2.**
The frailty cycle VO₂ = volume of oxygen utilisation. Reproduced with permission from The McGraw-Hill Companies.

See this image and copyright information in PMC

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References

1. Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006;54:991–1001. doi: 10.1111/j.1532-5415.2006.00745.x. - DOI - PubMed
1. Fried L, Walston J. Frailty and failure to thrive. In: Hazzard W, Blass J, Halter J, et al., editors. Principles of geriatric medicine and gerontology. 5th edn. New York: McGraw-Hill; 2003.
1. Strandberg TE, Pitkälä KH. Frailty in elderly people. Lancet. 2007;369:1328–9. doi: 10.1016/S0140-6736(07)60613-8. - DOI - PubMed
1. Stuck AE, Siu AL, Wieland GD, Adams J, Rubenstein LZ. Comprehensive geriatric assessment: a meta-analysis of controlled trials. Lancet. 1993;342:1032–6. doi: 10.1016/0140-6736(93)92884-V. - DOI - PubMed
1. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–23. doi: 10.1093/ageing/afq034. - DOI - PMC - PubMed

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[1] Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006;54:991–1001. doi: 10.1111/j.1532-5415.2006.00745.x. - DOI - PubMed

[2] Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006;54:991–1001. doi: 10.1111/j.1532-5415.2006.00745.x. - DOI - PubMed

[3] Fried L, Walston J. Frailty and failure to thrive. In: Hazzard W, Blass J, Halter J, et al., editors. Principles of geriatric medicine and gerontology. 5th edn. New York: McGraw-Hill; 2003.

[4] Fried L, Walston J. Frailty and failure to thrive. In: Hazzard W, Blass J, Halter J, et al., editors. Principles of geriatric medicine and gerontology. 5th edn. New York: McGraw-Hill; 2003.

[5] Strandberg TE, Pitkälä KH. Frailty in elderly people. Lancet. 2007;369:1328–9. doi: 10.1016/S0140-6736(07)60613-8. - DOI - PubMed

[6] Strandberg TE, Pitkälä KH. Frailty in elderly people. Lancet. 2007;369:1328–9. doi: 10.1016/S0140-6736(07)60613-8. - DOI - PubMed

[7] Stuck AE, Siu AL, Wieland GD, Adams J, Rubenstein LZ. Comprehensive geriatric assessment: a meta-analysis of controlled trials. Lancet. 1993;342:1032–6. doi: 10.1016/0140-6736(93)92884-V. - DOI - PubMed

[8] Stuck AE, Siu AL, Wieland GD, Adams J, Rubenstein LZ. Comprehensive geriatric assessment: a meta-analysis of controlled trials. Lancet. 1993;342:1032–6. doi: 10.1016/0140-6736(93)92884-V. - DOI - PubMed

[9] Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–23. doi: 10.1093/ageing/afq034. - DOI - PMC - PubMed

[10] Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–23. doi: 10.1093/ageing/afq034. - DOI - PMC - PubMed

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The frailty syndrome

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The frailty syndrome

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