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Review
. 2011 Feb;11(1):72-5.
doi: 10.7861/clinmedicine.11-1-72.

The frailty syndrome

Andrew Clegg  1 , John Young
Affiliations
Review

The frailty syndrome

Andrew Clegg et al. Clin Med (Lond). 2011 Feb.
No abstract available

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Figures

Fig 1.
Fig 1.
Vulnerability to sudden change in health state due to reduced functional reserve in frail older people. UTI = urinary tract infection
Fig 2.
Fig 2.
The frailty cycle VO2 = volume of oxygen utilisation. Reproduced with permission from The McGraw-Hill Companies.
See this image and copyright information in PMC

References

    1. Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006;54:991–1001. doi: 10.1111/j.1532-5415.2006.00745.x. - DOI - PubMed
    1. Fried L, Walston J. Frailty and failure to thrive. In: Hazzard W, Blass J, Halter J, et al., editors. Principles of geriatric medicine and gerontology. 5th edn. New York: McGraw-Hill; 2003.
    1. Strandberg TE, Pitkälä KH. Frailty in elderly people. Lancet. 2007;369:1328–9. doi: 10.1016/S0140-6736(07)60613-8. - DOI - PubMed
    1. Stuck AE, Siu AL, Wieland GD, Adams J, Rubenstein LZ. Comprehensive geriatric assessment: a meta-analysis of controlled trials. Lancet. 1993;342:1032–6. doi: 10.1016/0140-6736(93)92884-V. - DOI - PubMed
    1. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–23. doi: 10.1093/ageing/afq034. - DOI - PMC - PubMed