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Editorial
. 2011 May;10(3):337-40.
doi: 10.1517/14740338.2011.562187. Epub 2011 Mar 15.

Use of the self-controlled case series method in drug safety assessment

Anthony Grosso, Ian Douglas, Raymond MacAllister, Irene Petersen, Liam Smeeth, Aroon D Hingorani
Editorial

Use of the self-controlled case series method in drug safety assessment

Anthony Grosso et al. Expert Opin Drug Saf. 2011 May.
No abstract available

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Figures

Figure 1
Figure 1
Pictorial representation of a self-controlled case series method where age-adjusted incidence rate ratios of the outcome of interest are derived using Conditional Poisson Regression by comparing defined intervals during the exposure period relative to all other observed time [baseline period] for each person.
See this image and copyright information in PMC

References

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    1. Farrington P, Pugh S, Colville A, Flower A, Nash J, Morgan-Capner P, et al. A new method for active surveillance of adverse events from diphtheria/tetanus/pertussis and measles/mumps/rubella vaccines. Lancet. 1995;345(8949):567–569. - PubMed
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    1. Grosso A, Douglas I, Hingorani AD, MacAllister R, Hubbard R, Smeeth L. Inhaled tiotropium bromide and risk of stroke. Br J Clin Pharmacol. 2009;68(5):731–736. - PMC - PubMed
    1. Grosso A, Douglas I, Hingorani A, MacAllister R, Smeeth L. Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis. PLoS One. 2009;4(3):e4720. - PMC - PubMed

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