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Review
. 2011 Apr;18(2):158-64.
doi: 10.1016/j.tracli.2011.02.007. Epub 2011 Mar 15.

[In vitro platelet production]

[Article in French]
Affiliations
Review

[In vitro platelet production]

[Article in French]
C Dunois-Lardé et al. Transfus Clin Biol. 2011 Apr.

Abstract

This review aims at presenting a state of the art on platelet functions, not only in well-characterized hemostasis and thrombosis, but also in various domains such as inflammation, immunity, angiogenesis, source of growth factors, metastasis and vascular remodelling. This multivalent phenotype of platelets suggests new potential applications of platelets. The second objective is to present new advances in platelet formation from megakaryocytes and direct platelet release, as initially shown by our group and more recently by others.

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