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Comparative Study
. 2011 May;49(5):1956-60.
doi: 10.1128/JCM.00142-11. Epub 2011 Mar 16.

Comparison of Etest method with reference broth microdilution method for antimicrobial susceptibility testing of Yersinia pestis

David R Lonsway  1 , Sandra K Urich, Henry S Heine, Sigrid K McAllister, Shailen N Banerjee, Martin E Schriefer, Jean B Patel
Affiliations
Comparative Study

Comparison of Etest method with reference broth microdilution method for antimicrobial susceptibility testing of Yersinia pestis

David R Lonsway et al. J Clin Microbiol. 2011 May.

Abstract

The utility of Etest for antimicrobial susceptibility testing of Yersinia pestis was evaluated in comparison with broth microdilution and disk diffusion for eight agents. Four laboratories tested 26 diverse strains and found Etest to be reliable for testing antimicrobial agents used to treat Y. pestis, except for chloramphenicol and trimethoprim-sulfamethoxazole. Disk diffusion testing is not recommended.

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Figures

Fig. 1.
Fig. 1.
Numbers of MIC results obtained by using 48-h Etest and 48-h broth microdilution (BMD) for eight antimicrobial agents tested against 26 Y. pestis isolates at four test sites (n = 104). The lowest dilution tested by BMD is indicated for cases in which the value was different from the lowest dilution on the x axis. Trimethoprim-sulfamethoxazole MIC values indicate the trimethoprim portion only.
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References

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