Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2011 Apr;31(4):725-7.
doi: 10.1161/ATVBAHA.111.222976.

Drugs targeting epigenetic histone acetylation in vascular smooth muscle cells for restenosis and atherosclerosis

Editorial

Drugs targeting epigenetic histone acetylation in vascular smooth muscle cells for restenosis and atherosclerosis

Rama Natarajan. Arterioscler Thromb Vasc Biol. 2011 Apr.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Major cellular processes in vascular smooth muscle cells that are regulated by histone acetylation/deacetylation. SMC smooth muscle cells; HDAC Histone deacetylase; HAT Histone acetyltransferase; HDI Histone deacetylase inhibitor; Ang II Angiotensin II; MMP-2 Matrix metalloproteinase 2; IL-6 Interleukin 6

Comment on

References

    1. Ling C, Groop L. Epigenetics: a molecular link between environmental factors and type 2 diabetes. Diabetes. 2009;58:2718–2725. - PMC - PubMed
    1. Portela A, Esteller M. Epigenetic Modifications and human disease. Nat Biotechnol. 2010;28:1057–1068. - PubMed
    1. Villeneuve LM, Natarajan R. The role of epigenetics in the pathology of diabetic complications. Am J Physiol. 2010;299:F14–F25. - PMC - PubMed
    1. Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes Dev. 2009;23(7):781–783. - PMC - PubMed
    1. Kouzarides T. Chromatin modifications and their function. Cell. 2007;128:693–705. - PubMed

MeSH terms