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. 2011 Mar 11;6(3):e17448.
doi: 10.1371/journal.pone.0017448.

Predictors of retention among men attending STI clinics in HIV prevention programs and research: a case control study in Pune, India

Affiliations

Predictors of retention among men attending STI clinics in HIV prevention programs and research: a case control study in Pune, India

Seema Sahay et al. PLoS One. .

Abstract

Background: Retention is critical in HIV prevention programs and clinical research. We studied retention in the three modeled scenarios of primary prevention programs, cohort studies and clinical trials to identify predictors of retention.

Methodology/principal findings: Men attending Sexually Transmitted Infection (STI) clinics (n = 10, 801) were followed in a cohort study spanning over a ten year period (1993-2002) in Pune, India. Using pre-set definitions, cases with optimal retention in prevention program (n = 1286), cohort study (n = 940) and clinical trial (n = 896) were identified from this cohort. Equal number of controls matched for age and period of enrollment were selected. A case control analysis using conditional logistic regression was performed. Being employed was a predictor of lower retention in all the three modeled scenarios. Presence of genital ulcer disease (GUD), history of commercial sex work and living away from the family were predictors of lower retention in primary prevention, cohort study and clinical trial models respectively. Alcohol consumption predicted lower retention in cohort study and clinical trial models. Married monogamous men were less likely to be retained in the primary prevention and cohort study models.

Conclusions/significance: Predicting potential drop-outs among the beneficiaries or research participants at entry point in the prevention programs and research respectively is possible. Suitable interventions might help in optimizing retention. Customized counseling to prepare the clients properly may help in their retention.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Predictors of retention in the modeled scenario of primary prevention (1a), cohort study (1b) and clinical trial (1c).

References

    1. NACO. Department of AIDS control- Ministry of health and family welfare. Annual report 2009–2010 - Available: http://nacoonline.org/upload/AR%202009-10/NACO_AR_English%20corrected.pdf. Accessed 2011 Feb 9.
    1. Rao S. Towards containing HIV/ AIDS epidemic in India: policies and priorities under National AIDS Control Program Phase-III (2007–2012). J Indian Med Assoc. 2009;107(5):274–275. - PubMed
    1. Hecht R, Bollinger L, Stover J, McGreevey W, Muhib, et al. Critical Choices in financing the response to the global HIV/AIDS pandemic. Health Affairs. 2009;28(6):1591–1605. - PubMed
    1. Padian N, van der Straten A, Ramjee G, Chipato T, de Bruyn G, et al. Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: A randomized controlled trial. Lancet. 2007;370:251–261. - PMC - PubMed
    1. Villacorta V, Kegeles S, Galea J, Konda K, Cuba J, et al. Innovative approaches to cohort retention in a community-based HIV/STI prevention trial for socially marginalized Peruvian young adults. Clin Trials. 2007;4(1):32–41. - PMC - PubMed

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