Phototransduction in Rods and Cones
- PMID: 21413414
- Bookshelf ID: NBK52768
Phototransduction in Rods and Cones
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Sections
- 1. Introduction.
- 2. Structure of rods and cones.
- 3. Can we see a single photon?
- 4. Development of mouse photoreceptors
- 5. Vertebrate rods are highly efficient photon detectors
- 6. Phototransduction in rods: a G-protein-signaling pathway
- 7. Visual Pigments of Mouse Rods and Cones
- 8. High quantum efficiency of photoactivation
- 9. The activation of transducin constitutes the first amplification step
- 10. The high catalytic power of PDE accounts for the second amplification step
- 11. cGMP is the second messenger mediating rod phototransduction
- 12. The cGMP-gated channel provides the final step of photo-activation
- 13. Phototransduction termination
- 14. R* termination
- 15. G*-PDE* termination
- 17. Mouse model of cone phototransduction
- 18. Concluding remarks
- The author
- 19. References
References
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- Aho A.C. et al. Low retinal noise in animals with low body temperature allows high visual sensitivity. Nature. 1988;334(6180):348–50. [] - PubMed
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- Anant J.S. et al. In vivo differential prenylation of retinal cyclic GMP phosphodiesterase catalytic subunits. J Biol Chem. 1992;267(2):687–90. [] - PubMed
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- Angleson J.K., Wensel T.G. Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase. J Biol Chem. 1994;269(23):16290–6. [] - PubMed
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- Applebury M.L. et al. The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning. Neuron. 2000;27(3):513–23. [] - PubMed
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