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Case Reports
. 2011 Mar 7:2010:673908.
doi: 10.4061/2010/673908.

Kimura disease: a case report and review of the literature with a new management protocol

Mohamed Ashraf Fouda  1 , Osama Gheith, Ayman Refaie, Mohamed El-Saeed, Adel Bakr, Ehab Wafa, Mona Abdelraheem, Mohamed Sobh
Affiliations
Case Reports

Kimura disease: a case report and review of the literature with a new management protocol

Mohamed Ashraf Fouda et al. Int J Nephrol. .

Abstract

Kimura disease (KD) is a chronic inflammatory disorder with angiolymphatic proliferation, usually affecting young men of Asian race but is rare in other races. The etiology of KD is still unknown. It is often accompanied by nephrotic syndrome. Herein, we present an atypical manifestation of Kimura disease occurring in a Caucasian man with steroid-responsive early membranous glomerulonephritis. Kimura disease can present atypically in a middle-aged Caucasian man with secondary steroid-responsive nephrotic syndrome. Steroid, endoxan, and MMF can be used safely and successfully in such situation. The diagnosis of KD can be difficult and misleading, and patients with this disease are often evaluated using avoidable procedures by just not being aware of KD.

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Figures

Figure 1
Figure 1
Irregular and thick basement membrane (H&E) and vaculizations of basement membrane of glomerulus (silver stain).
Figure 2
Figure 2
Eosinophilic interstitial infiltrates in renal tissue.
Figure 3
Figure 3
Eosinophilic infiltrates of skin lesion.
See this image and copyright information in PMC

References

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