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Review
. 2012 Aug;43(1-2):138-55.
doi: 10.1007/s12016-011-8260-4.

The adult asthmatic

Amir A Zeki  1 , Nicholas J Kenyon, Ken Yoneda, Samuel Louie
Affiliations
Review

The adult asthmatic

Amir A Zeki et al. Clin Rev Allergy Immunol. 2012 Aug.

Abstract

Asthma in the adult patient is a complex clinical syndrome. Multiple patient phenotypes and subphenotypes exist that contribute to disease heterogeneity. Whether adult asthma begins in utero, develops in childhood, or manifests for the first time in adulthood is not completely understood, nor are the mechanisms fully delineated. In this chapter, we update definitions that apply to this group, emphasize epidemiologic factors and pathogenic mechanisms, diagnosis, therapeutic options, and controversies regarding drug safety. Finally, we provide a brief discussion of biomarker technologies and novel therapies with the potential to impact adult-onset asthma outcomes.

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