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. 2011 Mar 23:8:133.
doi: 10.1186/1743-422X-8-133.

Outbreak of pandemic influenza A/H1N1 2009 in Nepal

Bal Ram Adhikari  1 , Geeta Shakya, Bishnu Prasad Upadhyay, Khagendra Prakash Kc, Sirjana Devi Shrestha, Guna Raj Dhungana
Affiliations

Outbreak of pandemic influenza A/H1N1 2009 in Nepal

Bal Ram Adhikari et al. Virol J. .

Abstract

Background: The 2009 flu pandemic is a global outbreak of a new strain of H1N1 influenza virus. Pandemic influenza A (H1N1) 2009 has posed a serious public health challenge world-wide. Nepal has started Laboratory diagnosis of Pandemic influenza A/H1N1 from mid June 2009 though active screening of febrile travellers with respiratory symptoms was started from April 27, 2009.

Results: Out of 609 collected samples, 302 (49.6%) were Universal Influenza A positive. Among the influenza A positive samples, 172(28.3%) were positive for Pandemic influenza A/H1N1 and 130 (21.3%) were Seasonal influenza A. Most of the pandemic cases (53%) were found among young people with ≤ 20 years. Case Fatality Ratio for Pandemic influenza A/H1N1 in Nepal was 1.74%. Upon Molecular characterization, all the isolated pandemic influenza A/H1N1 2009 virus found in Nepal were antigenically and genetically related to the novel influenza A/CALIFORNIA/07/2009-LIKE (H1N1)v type.

Conclusion: The Pandemic 2009 influenza virus found in Nepal were antigenically and genetically related to the novel A/CALIFORNIA/07/2009-LIKE (H1N1)v type.

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Figures

Figure 1
Figure 1
The neighbor joining tree of influenza A/H1N1 (Swine) 2009 complete HA gene (1,701 bp).
Figure 2
Figure 2
Epidemic curve of Confirmed cases of Pandemic influenza A/H1N1 2009 (n = 172).
Figure 3
Figure 3
Travel history of confirmed Pandemic influenza A/H1N1cases before community transmission (n = 36).
Figure 4
Figure 4
District wise distribution of total Pandemic influenza A/H1N1 cases after community transmission (n = 136).
Figure 5
Figure 5
Age wise distribution of confirmed Pandemic influenza A/H1N1 cases (n = 172).
Figure 6
Figure 6
Sex wise distribution of confirmed Pandemic influenza A/H1N1 cases (n = 172).
Figure 7
Figure 7
Information of death cases in Nepal by Pandemic influenza A/H1N1.
See this image and copyright information in PMC

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