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. 2011 Jun;158(6):878-884.e1.
doi: 10.1016/j.jpeds.2011.01.057. Epub 2011 Mar 22.

Phenotypic expressions of childhood wheezing and asthma: implications for therapy

Bradley E Chipps  1 , Leonard B Bacharier, Julia M Harder
Affiliations

Phenotypic expressions of childhood wheezing and asthma: implications for therapy

Bradley E Chipps et al. J Pediatr. 2011 Jun.
No abstract available

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Figures

Figure 1
Figure 1
The modified Asthma Predictive Index. The presence of one major criterion or two minor criteria indicates a high likelihood that the infant or child will have persistent asthma.
Figure 2
Figure 2
Bimonthly proportion of episode-free days during the 2-year treatment period and the observation period in the Prevention of Early Asthma in Kids (PEAK) study. Fluticasone treatment, as compared with placebo, did not increase the proportion of episode-free days during the observation year, but during the 2-year treatment period (shaded area) it significantly increased the proportion of episode-free days.
Figure 3
Figure 3
The EPR-3 recommends a stepwise approach for managing asthma long-term in children A, ages 0 to 4 years B, 5 to 11 years C, and 12 years and older. PRN indicates as needed.
Figure 4
Figure 4
Prevalence of current wheeze from birth to age 13 years in children with any wheezing episode at school age (5 to 7 years), stratified by atopy at school age.
Figure 5
Figure 5
Health care utilization by number of long-term controller medications in patients ages 6 to 11 years (left panel) and 12 to 17 years (right panel) in the TENOR study. Long-term controllers include inhaled corticosteroids, LABA, leukotriene modifiers, methylxanthines, and cromolyn sodium or nedocromil. ED, emergency department.
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