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. 2011 May;49(5):2000-2.
doi: 10.1128/JCM.00249-11. Epub 2011 Mar 23.

Serum (1->3)-beta-D-glucan levels in primary infection and pulmonary colonization with Pneumocystis jirovecii

Céline Damiani  1 , Solène Le Gal, Delphine Lejeune, Naima Brahimi, Michèle Virmaux, Gilles Nevez, Anne Totet
Affiliations

Serum (1->3)-beta-D-glucan levels in primary infection and pulmonary colonization with Pneumocystis jirovecii

Céline Damiani et al. J Clin Microbiol. 2011 May.

Abstract

This article describes positive (1 → 3)-β-D-glucan levels in serum from infants with primary Pneumocystis infection and from immunosuppressed patients with Pneumocystis pneumonia (PCP) and negative levels in serum from patients colonized by Pneumocystis jirovecii. Glucan detection is a complementary tool for the diagnosis of the diverse clinical presentations of P. jirovecii infection.

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Figures

Fig. 1.
Fig. 1.
Serum (1→3)-β-d-glucan levels in infants with primary Pneumocystis infection, patients with Pneumocystis colonization, patients with Pneumocystis pneumonia (PCP), and an infant control group. Serum BG levels were significantly higher in the PCP control group than in infants with primary infection (†, Student's test, P < 0.05) and colonized patients (‡, Wilcoxon's test, P < 0.05). Serum BG levels were significantly higher in infants with primary infection than in colonized patients (†, Student's test, P < 0.05).
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