AMP kinase signals the insulin-like growth factor system whether adequate nutrient is present to support an anabolic response
- PMID: 21430440
- DOI: 10.4161/cc.10.7.15088
AMP kinase signals the insulin-like growth factor system whether adequate nutrient is present to support an anabolic response
Comment on
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AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation.Mol Endocrinol. 2010 Jun;24(6):1218-29. doi: 10.1210/me.2009-0474. Epub 2010 Apr 2. Mol Endocrinol. 2010. PMID: 20363874 Free PMC article.