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. 2001 Jul;6(2):82-7.
doi: 10.1007/BF02897950.

The unique correlation between anti-mutagenicity of human saliva and change in body weight

M Toda  1 , K Morimoto, S Nakamura, T Umeda, S Nakaji, K Sugawara
Affiliations

The unique correlation between anti-mutagenicity of human saliva and change in body weight

M Toda et al. Environ Health Prev Med. 2001 Jul.

Abstract

The purpose of this study was to investigate the effect of weight reduction on the anti-mutagenicity of human saliva. Subjects were 16 male college judo players. The anti-mutagenicity of the saliva was measured using the umu test. There was an inhibiting effect of the saliva on the mutagenicity of AF-2. However, a modifying effect of the saliva on Trp-P-1 was not observed. On the day before a competition and 7 days after the competition, the inhibiting capacity of the saliva for the mutagenicity of AF-2 decreased and increased in two non-weight reduction and two weight reduction groups, respectively.However, on the day before the competition, the changed body weights (r=-0.77, p<0.01) and BMI (r=-0.77, p<0.01) were significantly correlated with that of the inhibiting capacity of the saliva for the mutagenicity of AF-2. In addition, the BMI at 20 days before the competition was not significantly but markedly correlated with it (r=0.50, p=0.057). At 7 days after the competition, however, these correlations were not found.These findings suggest a unique correlation between the anti-mutagenicity of human saliva and body weight or BMI.

Keywords: anti-mutagenicity; fasting; human saliva; judo players; umu test.

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