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. 2002 Sep;7(4):169-72.
doi: 10.1007/BF02897946.

The impacts of health examinations and smoking on disease mortality risk in Japan: a longitudinal cohort of 720,611 Japanese life insured persons

Machi Suka  1 , Hiroki Sugimori, Katsumi Yoshida
Affiliations

The impacts of health examinations and smoking on disease mortality risk in Japan: a longitudinal cohort of 720,611 Japanese life insured persons

Machi Suka et al. Environ Health Prev Med. 2002 Sep.

Abstract

Objectives: To evaluate the impacts of health examinations (HE) and smoking on disease mortality risk in Japan.

Methods: By using the large cohort database of a Japanese life insurance company, 720,611 subjects aged 20 to 80 years, who had contracted for life insurance between April 1, 1995 and March 31, 1998, were followed up until September 30, 1999. Cox's proportional hazard model was used to estimate age-adjusted relative risk (RR) for disease death.

Results: After adjusting for age, disease mortality in smokers was significantly higher than that in non-smokers (men, RR 1.51, 95% CI: 1.25-1.81; women, RR 1.54, 95% CI: 1.12-2.11). Meanwhile, disease mortality in HEees (those who had got HE within the past 2 years) was significantly lower than that in non-HEees (men, RR 0.70, 95% CI: 0.56-0.88; women, RR 0.71, 95% CI: 0.54-0.92). The magnitude of the impact of HE on disease mortality risk varied according to smoking status. Non-smokers showed a significantly lower risk associated with HE, whereas smokers did not.

Conclusions: HE may allow an appreciable reduction in disease mortality, however, the reduction effect may be limited to non-smokers. Smoking cessation may be essential to improve the preventive effects of HE.

Keywords: cohort study; health examination; mortality; smoking.

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References

    1. Health and Welfare Ministry. Healthy Japan 21. Available at: http://www.kenkounippon21.gr.jp/index.html (Japanese)
    1. None
    2. U.S. Preventive Services Task Force. Guide to clinical preventive services: report of the U.S. Preventive Services Task Force. 2nd edition. Baltimore: Williams & Wilkins, 1996.
    1. None
    2. Health and Welfare Statistics Association. Trend of National Health 2001. Tokyo: Health and Welfare Statistics Association, 2001. (Japanese)
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1001/archinte.159.7.733', 'is_inner': False, 'url': 'https://doi.org/10.1001/archinte.159.7.733'}, {'type': 'PubMed', 'value': '10218754', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/10218754/'}]}
    2. Jacobs DR, Adachi H, Mulder I, et al. Cigarette smoking and mortality risk. Twenty-five-year follow-up of the seven countries study. Arch. Intern. Med. 1999; 159: 733–740. - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/0091-7435(91)90060-H', 'is_inner': False, 'url': 'https://doi.org/10.1016/0091-7435(91)90060-h'}, {'type': 'PubMed', 'value': '1758843', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/1758843/'}]}
    2. Kuller LH, Ockene JK, Meilahn E, Wentworth DN, Svendsen KH, Neaton JD. Cigarette smoking and mortality. Prev. Med. 1991; 20: 638–654. - PubMed