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. 2002 Nov;7(5):183-8.
doi: 10.1007/BF02898002.

Efficacy of influenza vaccine among elderly patients by physical activity status

Yuichi Hara  1 , Akihito Hagihara, Hideyuki Ikematu, Koichi Nobutomo
Affiliations

Efficacy of influenza vaccine among elderly patients by physical activity status

Yuichi Hara et al. Environ Health Prev Med. 2002 Nov.

Abstract

Objective: Although many studies have shown the usefulness of influenza vaccine in elderly in-patients, the efficacy of vaccination with regard to the daily physical activities of patients has not been fully evaluated. To address this issue, we correlated the use of medical resources with vaccination status in patients categorized according to their daily activity levels.

Methods: The subjects comprised 237 in-patients at or above 51 years of age, who were hospitalized in the long-term care unit of a Japanese hospital between January and March, 1999. The vaccination status and medical resources use (i.e., oral antibiotics, injected antibiotics, blood cell count, chest X-ray) of each patient were recorded, and the patients were assigned to three subgroups, based on daily life activity scores.

Results: Vaccinated in-patients in the 'bed-bound' category required fewer medical resources, i.e., oral antibiotics (-2.29 days,P<0.05), injected antibiotics (-5.02 days,P<0.001), blood cell counts (-4.66 times,P<0.001), and chest X-rays (-4.31 times,P<0.001), compared with unvaccinated in-patients. There were no significant differences in treatment parameters between vaccinated and unvaccinated patients in the 'partly limited' or 'no limitation' categories.

Conclusions: It is suggested that influenza vaccination significantly reduces the need for medical treatment only among those in-patients who are the least physically active. Further studies are required to replicate these findings, and to elucidate the underlying reasons for this reduction.

Keywords: daily activity; efficacy; elderly; influenza vaccine; long-term care unit.

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References

    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PMC', 'value': 'PMC1646876', 'is_inner': False, 'url': 'https://pmc.ncbi.nlm.nih.gov/articles/PMC1646876/'}, {'type': 'PubMed', 'value': '3717461', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/3717461/'}]}
    2. Barker WH. Excess pneumonia- and influenza-associated hospitalizations during influenza epidemics in the United States, 1970–1978. Am. J. Public Health 1986; 76: 761–765. - PMC - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PubMed', 'value': '1462665', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/1462665/'}]}
    2. Ghendon Y. Influenza—its impact and control. World Health Stat Q 1992; 45: 306–311. - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/0264-410X(89)90190-4', 'is_inner': False, 'url': 'https://doi.org/10.1016/0264-410x(89)90190-4'}, {'type': 'PubMed', 'value': '2815966', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/2815966/'}]}
    2. Gross PA, Quinnan GV Jr, Weksler ME, Setia U, Douglas RG Jr. Relation of chronic disease and immune response to influenza vaccine in the elderly. Vaccine 1989; 7: 303–308. - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1093/ageing/28.2.141', 'is_inner': False, 'url': 'https://doi.org/10.1093/ageing/28.2.141'}, {'type': 'PubMed', 'value': '10350410', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/10350410/'}]}
    2. Potter JM, O’Donnell B, Carman WF, Roberts MA, Stott DJ. Serological response to influenza vaccination and nutritional and functional status of patients in geriatric medical long-term care. Age Aging 1999; 28: 141–145. - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/S0264-410X(99)00507-1', 'is_inner': False, 'url': 'https://doi.org/10.1016/s0264-410x(99)00507-1'}, {'type': 'PubMed', 'value': '10689149', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/10689149/'}]}
    2. Webster RG. Immunity of influenza in the elderly. Vaccine 2000; 18: 1686–1689. - PubMed