Silibinin mode of action against hepatitis C virus: a controversy yet to be resolved
- PMID: 21433039
- PMCID: PMC3677944
- DOI: 10.1002/hep.24310
Silibinin mode of action against hepatitis C virus: a controversy yet to be resolved
Conflict of interest statement
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Comment on
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Multiple effects of silymarin on the hepatitis C virus lifecycle.Hepatology. 2010 Jun;51(6):1912-21. doi: 10.1002/hep.23587. Hepatology. 2010. PMID: 20512985 Free PMC article.
References
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- Ahmed-Belkacem A, Ahnou N, Barbotte L, et al. Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase. Gastroenterology. 2010 Mar;138(3):1112–1122. - PubMed
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- Ferenci P, Scherzer TM, Kerschner H, et al. Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy. Gastroenterology. 2008 Nov;135(5):1561–1567. - PubMed
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- Biermer M, Berg T. Rapid suppression of hepatitis C viremia induced by intravenous silibinin plus ribavirin. Gastroenterology. 2009 Jul;137(1):390–391. - PubMed
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