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Review
. 2011 Jun 30;95(8):2527-30.
doi: 10.1016/j.fertnstert.2011.02.040. Epub 2011 Mar 24.

Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials

Lisa Dapuzzo  1 , Faith E Seitz, William C Dodson, Christina Stetter, Allen R Kunselman, Richard S Legro
Affiliations
Review

Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials

Lisa Dapuzzo et al. Fertil Steril. .

Abstract

Pregnancy outcomes and adverse outcomes in infertility trials are reported to varying extents; for example, 35% of clinical trials reported no information on pregnancy loss, only 43% reported adverse events during the preconception treatment period, and only 7% reported any serious adverse events. Incomplete reporting limits the value of these studies in counseling patients on the risk-benefit ratio of treatment to themselves and their infants.

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Conflict of interest statement

Conflicts of Interest: The authors report no conflicts of interest.

Figures

Figure 1
Figure 1
Flow chart of articles retrieved from the top impact journals in Obstetrics and Gynecology for this review.
Figure 2
Figure 2
The proportion of articles reporting the events of interest, e.g., pregnancy and live birth, multiple pregnancy, adverse events, etc. was calculated. with exact 95% confidence limits. Conception was defined as any positive serum hCG level, a pregnancy was defined as an intrauterine pregnancy with fetal heart motion as determined by transvaginal ultrasound, and live birth was defined as delivery of any viable infant. (IUP = intrauterine pregnancy)
See this image and copyright information in PMC

References

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