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Case Reports
. 2011 Mar 18;11(1):19-22.
doi: 10.1102/1470-7330.2011.0005.

Omental inflammatory myofibroblastic tumour mimicking peritoneal carcinomatosis

Manphool Singhal  1 , Subramaniyan Ramanathan, Ashim Das, Gurpreet Singh, Rashmi Bagga, Niranjan Khandelwal
Affiliations
Case Reports

Omental inflammatory myofibroblastic tumour mimicking peritoneal carcinomatosis

Manphool Singhal et al. Cancer Imaging. .

Abstract

Inflammatory myofibroblastic tumour (IMFT) is a relatively uncommon neoplasm with unpredictable malignant potential known to occur anywhere in the body. IMFT involving the omentum is a very rare entity with less than 15 cases reported so far. We report a case of omental IMFT in a 15-year-old girl who presented with multiple peritoneal masses on imaging and the diagnosis was confirmed on histopathology. In addition to its uncommon location, its presentation as multiple masses is extremely uncommon. This uncommon presentation as multifocal masses needs to be distinguished from other causes of peritoneal carcinomatosis.

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Figures

Figure 1
Figure 1
US images show heterogeneous hypoechoic lesions in the pelvis (a) and on the parietal peritoneum (c). Note internal vascularity on colour Doppler (b,d).
Figure 2
Figure 2
Contrast-enhanced CT images show a lobulated hypervascular lesion in the pelvis with free fluid (a). Note multiple peritoneal-based lesions (arrows) (b–d).
Figure 3
Figure 3
(a) The periphery of the tumour with infiltration into fat (H&E); (b) spindle-shaped tumour cells in short interlacing fascicles admixed with moderate chronic inflammatory cells rich in plasma cells (H&E); (c) spindle cell populations with plasma cell infiltrate with the tumour cells showing cytoplasmic ALK positivity (inset: ALK immunostaining); and (d) some tumour cells are elongated with abundant eosinophilic cytoplasm (H&E) showing SMA positivity (inset: SMA immunostaining) indicating the myofibroblastic nature.
See this image and copyright information in PMC

References

    1. Treissman SP, Gillis DA, Lee CL, et al. Omental-mesenteric inflammatory pseudotumor. Cytogenetic demonstration of genetic changes and monoclonality in one tumor. Cancer. 1994;73:1433–7. doi: 10.1002/1097-0142(19940301)73:5<1433::AID-CNCR2820730518>3.0.CO;2-F. . PMid:8111710. - DOI - PubMed
    1. Meis JM, Enzinger FM. Inflammatory fibrosarcoma of the mesentery and retroperitoneum. A tumor closely simulating inflammatory pseudotumor. Am J Surg Pathol. 1991;15:1146–56. doi: 10.1097/00000478-199112000-00005. . PMid:1746682. - DOI - PubMed
    1. Day DL SS, Dehner LP. Inflammatory pseudotumor of the mesentery and small intestine. Pediatr Radiol. 1986;16:210–15. doi: 10.1007/BF02456289. . PMid:3703596. - DOI - PubMed
    1. Kim SJ, Kim WS, Cheon JE, et al. Inflammatory myofibroblastic tumors of the abdomen as mimickers of malignancy: imaging features in nine children. AJR Am J Roentgenol. 2009;193:1419–24. doi: 10.2214/AJR.09.2433. . PMid:19843762. - DOI - PubMed
    1. Levy AD, Shaw JC, Sobin LH. Secondary tumors and tumorlike lesions of the peritoneal cavity: imaging features with pathologic correlation. Radiographics. 2009;29:347–73. doi: 10.1148/rg.292085189. . PMid:19325052. - DOI - PubMed

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