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. 2009 Sep 9:2:155-63.

Self-monitoring of blood glucose in noninsulin-treated type 2 diabetes: an overview

Nanne Kleefstra  1 , Johanna Hortensius, Kornelis Jj van Hateren, Susan Jj Logtenberg, Sebastiaan T Houweling, Rijk Ob Gans, Henk Jg Bilo
Affiliations

Self-monitoring of blood glucose in noninsulin-treated type 2 diabetes: an overview

Nanne Kleefstra et al. Diabetes Metab Syndr Obes. .

Abstract

Introduction: The effectiveness of self-monitoring of blood glucose (SMBG) in noninsulin-treated patients with type 2 diabetes (T2DM) remains unclear. We aimed to review the trials investigating the effects of SMBG in this population.

Methods: Medline was searched until June 29, 2009. Randomized controlled trials (RCTs) of at least 12 weeks' duration were included. Data on the following aspects were gathered: patient and study characteristics, effects on HbA(1c), quality of life and treatment satisfaction, and methodological quality.

Results: The search revealed 9 original RCTs. These studies were very heterogeneous, and 5 were classified as of high quality. The studies with the best methodology did not show an effect of SMBG on HbA(1c), the studies with the worst methodological quality did. Two out of the 4 studies that assessed quality of life showed a significant change in favor of the control group, 1 study showed a significant change in favor of SMBG.

Discussion and conclusion: We found an inverse relation between study quality and efficacy of SMBG. At this moment, there is no basis for general use of SMBG in noninsulin-treated T2DM patients.

Keywords: blood glucose; blood glucose self-monitoring; diabetes mellitus; glycosylated; hemoglobin A; type 2.

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References

    1. Goldstein DE, Little RR, Lorenz RA, et al. Tests of glycemia in diabetes. Diabetes Care. 2004;27(7):1761–1773. - PubMed
    1. Nathan DM, McKitrick C, Larkin M, Schaffran R, Singer DE. Glycemic control in diabetes mellitus: have changes in therapy made a difference? Am J Med. 1996;100(2):157–163. - PubMed
    1. Karter AJ, Ackerson LM, Darbinian JA, et al. Self-monitoring of blood glucose levels and glycemic control: the Northern California Kaiser Permanente Diabetes registry. Am J Med. 2001;111(1):1–9. - PubMed
    1. Welschen LM, Bloemendal E, Nijpels G, et al. Self-monitoring of blood glucose in patients with type 2 diabetes who are not using insulin. Cochrane Database Syst Rev. 2005;18(2):CD005060. - PubMed
    1. Farmer AJ, Heneghan C, Barnett AH, et al. Self-monitoring of blood glucose trialists collaboration. Individual patient data meta-analysis of trials of self-monitoring of blood glucose in noninsulin treated type 2 diabetes: Protocol for a systematic review. Prim Care Diabetes. Epub 2009 Apr 15. - PubMed

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