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. 2011;66(1):163-5.
doi: 10.1590/s1807-59322011000100028.

IDH1 mutations in a Brazilian series of Glioblastoma

Miyuki Uno  1 , Sueli Mieko Oba-Shinjo, Roseli da Silva, Flavio Miura, Carlos Afonso Clara, José Reynaldo Walther de Almeida, Suzana M F Malheiros, André Macedo Bianco, Reynaldo Brandt, Guilherme Carvalhal Ribas, Halim Feres, Carlos Dzik, Sérgio Rosemberg, João Norberto Stavale, Manoel Jacobsen Teixeira, Suely K N Marie
Affiliations

IDH1 mutations in a Brazilian series of Glioblastoma

Miyuki Uno et al. Clinics (Sao Paulo). 2011.
No abstract available

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Figures

Figure 1
Figure 1
Survival of glioblastoma patients according to their IDH1 mutation status (positive vs. negative). Glioblastoma patients carrying an IDH1 mutation had longer overall survival (log‐rank test; Mantel–Cox test; p = 0.075).
See this image and copyright information in PMC

References

    1. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007;114:97–109. 10.1007/s00401‐007‐0243‐4 - DOI - PMC - PubMed
    1. von Deimling A, Louis DN, Schramm J, Wiestler OD. Astrocytic gliomas: characterization on a molecular genetic basis. Recent Results Cancer Res. 1994:33–42. - PubMed
    1. Korshunov A, Sycheva R, Golanov A. The prognostic relevance of molecular alterations in glioblastomas for patients age <50 years. Cancer. 2005;104:825–32. 10.1002/cncr.21221 - DOI - PubMed
    1. Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, von Deimling A. Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol. 2008;116:597–602. 10.1007/s00401‐008‐0455‐2 - DOI - PubMed
    1. Ichimura K, Pearson DM, Kocialkowski S, Bäcklund LM, Chan R, Jones DT, et al. IDH1 mutations are present in the majority of common adult gliomas but are rare in primary glioblastomas. Neurol Oncol. 2009;11:341–7. 10.1215/15228517‐2009‐025 - DOI - PMC - PubMed

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