Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 Mar 25;18(3):277-8.
doi: 10.1016/j.chembiol.2011.03.002.

JAK3 specific kinase inhibitors: when specificity is not enough

Luk Cox  1 , Jan Cools
Affiliations
Comment

JAK3 specific kinase inhibitors: when specificity is not enough

Luk Cox et al. Chem Biol. .

Abstract

Janus kinases are important signaling proteins implicated in cytokine signaling. In particular, Janus kinase 3 (JAK3) has gained attention as a target for inhibition of the immune system, due to its importance for T and B cell development and function. In this issue however, Haan et al. (2011) show that inhibition of JAK3 activity may not be sufficient for this purpose.

PubMed Disclaimer

Comment on

LinkOut - more resources