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Review
. 2011 Apr;27(2):407-19.
doi: 10.1016/j.ccc.2010.12.012.

Biomarkers: the future

Affiliations
Review

Biomarkers: the future

Steven P LaRosa et al. Crit Care Clin. 2011 Apr.

Abstract

The future application of biomarkers in critical illness will be to select and guide therapy. Specific biomarkers could identify a pathophysiologic perturbation or noxious mediator to counteract or the need to replete a deficient protective protein. Functional genomics could identify patients at risk for illness or at risk for a poor outcome in critical illness. Genetic expression studies could help differentiate patients with sepsis from those with noninfectious inflammation and could also help to monitor illnesses over time. Expressional and functional proteomics could lead to the identification of new biomarkers and organ-specific therapies.

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