Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Mar;133(3):316-21.

Rapid spread of chikungunya virus infection in Orissa: India

B Dwibedi  1 , J Sabat, N Mahapatra, S K Kar, A S Kerketta, R K Hazra, S K Parida, N S Marai, M K Beuria
Affiliations

Rapid spread of chikungunya virus infection in Orissa: India

B Dwibedi et al. Indian J Med Res. 2011 Mar.

Abstract

Background & objectives: A large number of cases of undiagnosed fever and joint pain were reported from different parts of the State of Orissa since February 2006. Epidemiological and laboratory investigation were carried out to confirm the cause of emerging illness, which was provisionally suspected as Chikungunya (CHIK) fever.

Methods: Upon getting the reports of suspected CHIK like illness in different parts of the State, epidemic investigations were carried out in the outbreak affected villages. Case history was recorded, clinical examination undertaken and blood samples collected for seroconfirmation for CHIK IgM antibody using ELISA based kit. Simultaneously vector survey was also carried out.

Results: With no previous record of CHIK infection in the State, the first outbreak was confirmed during February 2006. Subsequently, the infection spread to 13 of 30 districts in different episodes covering 79 villages till November 2007. Attack rate was 9-43 per cent in the different outbreaks with average seropositivity of 24 per cent to CHIK specific IgM. Morbidity was high though no deaths were recorded. Aedes aegypti and Ae. albopictus were identified as the possible vectors for transmission.

Interpretation & conclusions: The report confirmed emergence of CHIK infection in the State of Orissa, India, and its spread to a larger geographic zone in a short period which warrants public health measures to control further spread.

PubMed Disclaimer

Figures

Fig
Fig
Epidemic curve showing week-wise onset of CHIK cases in Orissa (2006-2007).
See this image and copyright information in PMC

References

    1. Strauss EG, Strauss JH. Structure and replication of the alphavirus genome. In: Schlesinger S, Schlesinger MJ, editors. The togaviridae and flaviviridae. New York: Plenum Press; 1986. pp. 35–90.
    1. Porterfield JH. Schlesinger R, editor. Antigenic characteristics and classification of the Togaviridae. The togaviruses. 1980:13–46.
    1. Ross RW. The Newala epidemic III. The virus: Isolation, pathogenic properties and relationship to the epidemic. J Hyg. 1956;54:177–91. - PMC - PubMed
    1. Yergolkar PN, Tandale BV, Arankalle VA, Sathe PS, Sudeep AB, Gandhe SS, et al. CHIK outbreaks caused by African genotype, India. Emerg Infect Dis. 2006;12:1580–3. - PMC - PubMed
    1. Kalantri SP, Joshi R, Riley LW. CHIK epidemic: An Indian perspective. Natl Med J India. 2006;19:315–22. - PubMed

Publication types

MeSH terms