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. 2011 Mar 14:5:133-9.
doi: 10.2147/PPA.S11251.

Hyaluronic acid dermal fillers: can adjunctive lidocaine improve patient satisfaction without decreasing efficacy or duration?

Lynnelle Smith  1 , Kimberly Cockerham
Affiliations

Hyaluronic acid dermal fillers: can adjunctive lidocaine improve patient satisfaction without decreasing efficacy or duration?

Lynnelle Smith et al. Patient Prefer Adherence. .

Abstract

Hyaluronic acid (HA) dermal fillers are the most widely used injectables to augment facial volume without surgery. HA dermal fillers are popular because of their ease of administration, predictable effectiveness, good safety profile, and quick patient recovery. The most common patient complaint is pain. Our goal is to review the current literature on HA fillers and compare outcomes with and without lidocaine. We found adjunctive lidocaine significantly decreases pain during injection and postinjection with corresponding increased patient satisfaction. The efficacy and safety profile appears unchanged. Rare complications with HA fillers and those associated with constituents of the product, contaminants, and lidocaine are reviewed. The corrective effects of HA fillers are temporary; repeat treatment is required to maintain results. Minimizing pain is crucial to optimize patient satisfaction.

Keywords: collagen; drug toxicity; herpes simplex; hyaluronic acid; hypersensitivity; lidocaine.

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References

    1. Levy PM, de Boulle K, Raspaldo H. A split-face comparison of a new hyaluronic acid facial filler containing pre-incorporated lidocaine versus a standard hyaluronic acid facial filler in the treatment of naso-labial folds. J Cosmet Laser Ther. 2009;11(3):169–173. - PubMed
    1. Beasley KL, Weiss MA, Weiss RA. Soft tissue augmentation using a two-way connector to supplement hyaluronic acid filler with 1% lidocaine hydrochloric acid with epinephrine 1:100,000: our experience and observations. Dermatol Surg. 2010;36(4):524–526. - PubMed
    1. Levy PM, de Boulle K, Raspaldo H. Comparison of injection comfort of a new category of cohesive hyaluronic acid filler with preincorporated lidocaine and a hyaluronic acid filler alone. Dermatol Surg. 2009;35(Suppl 1):332–336. discussion 337. - PubMed
    1. Monheit GD, Campbell RM, Neugent H, et al. Reduced pain with use of proprietary hyaluronic acid with lidocaine for correction of nasolabial folds: a patient-blinded, prospective, randomized controlled trial. Dermatol Surg. 2010;36(1):94–101. - PubMed
    1. Research B. Cosmetic surgery markets: products and services. Last updated 2008. Available from: http://www.reportlinker.com/p0132720/Cosmetic-Surgery-Markets-Products-a.... Accessed October 8, 2010.