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. 2011 Jan 19:4:23-34.
doi: 10.2147/DMSO.S8540.

Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes

Latika Sibal  1 , Sharad C Agarwal, Philip D Home
Affiliations

Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes

Latika Sibal et al. Diabetes Metab Syndr Obes. .

Abstract

Background: Diabetes mellitus is associated with a high risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points.

Methods: This review examines the evidence linking CIMT as a surrogate marker of vascular complications in people with type 1 and type 2 diabetes. We have also reviewed the various treatment strategies which have been shown to influence CIMT.

Conclusions: CIMT measurement is an effective, noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to evaluate the effectiveness of various treatment strategies used to treat people with diabetes.

Keywords: CIMT; carotid; diabetes; intima-media thickness.

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Figures

Figure 1
Figure 1
Carotid intima-media thickness measured at the far wall of the common carotid artery using the double-line pattern.
See this image and copyright information in PMC

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