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. 2011 May-Jun;42(3):190-5.
doi: 10.3928/15428877-20110324-03. Epub 2011 Mar 31.

Can topical ketorolac 0.5% improve the function of Ahmed® glaucoma drainage devices?

Garrett R Scott  1 , Jennifer S Weizer, Sayoko E Moroi, Christina A Bruno, David C Musch, Leslie M Niziol, Paul P Lee, Joshua D Stein
Affiliations

Can topical ketorolac 0.5% improve the function of Ahmed® glaucoma drainage devices?

Garrett R Scott et al. Ophthalmic Surg Lasers Imaging. 2011 May-Jun.

Abstract

Background and objective: To determine whether postoperative use of topical ketorolac tromethamine 0.5% affects intraocular pressure (IOP) following Ahmed glaucoma drainage device (New World Medical, Inc., Rancho Cucamonga, CA) implantation.

Patients and methods: Patients undergoing Ahmed implantation at the University of Michigan from January 2002 to June 2008 were reviewed. Fourteen eyes received ketorolac after surgery; 50 eyes did not. Preoperative and postoperative IOP and glaucoma medications were recorded for both groups; the two-sided Student's t test was used to compare these parameters.

Results: Mean preoperative IOP was similar in the two groups (35.1 ± 11.9 vs 37.0 ± 12.2 mm Hg; P = .60). At postoperative month 6, the ketorolac group had significantly lower IOP compared with the no ketorolac group (13.1 ± 3.7 vs 19.5 ± 9.3 mm Hg, respectively; P = .0003). There was no difference in the number of glaucoma medications postoperatively between the two groups.

Conclusion: Ketorolac may lead to lower postoperative IOP following Ahmed implantation.

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Figures

Figure 1
Figure 1
Intraocular pressure over time by ketorolac use.
Figure 2
Figure 2
Number of glaucoma medications over time by ketorolac use.
See this image and copyright information in PMC

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